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PTSD: National Center for PTSD

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John H. Krystal, MD

 

John H. Krystal, MD

John H. Krystal, MD

Director

Clinical Neurosciences Division

See staff directory for contact information.


Academic Appointment

  • Yale University School of Medicine, Robert L. McNeil Jr. Professor of Psychiatry and Professor of Neurobiology; Chair, Department of Psychiatry

Education

  • Residency in Psychiatry, Yale University School of Medicine, 1984-1988
  • Internship, Hospital of St. Raphael, 1984-1985
  • Yale University, M.D., 1984
  • University of Chicago, B.A., 1980

Expertise and Interests

  • Neurobiology of PTSD (PET, MRS, MRI, EEG, experimental psychopharmacology)
  • Genetics of PTSD/resilience
  • Pharmacotherapy of PTSD

Membership in Professional Societies

  • Editor, Biological Psychiatry
  • Past-president, American College of Neuropsychopharmacology
  • Board of Directors (past/current): International Society of Traumatic Stress Studies, Research Society on Alcoholism, Society of Biological Psychiatry, Molecular Psychiatry Society
  • National Service (selected list): Department of Defense "Defense Health Board" Psychological Health Subcommittee, Chair of the NIMH Board of Scientific Counselors, Member of the National Alcohol Advisory Panel (NIAAA Council)
  • Institute of Medicine, National Academy of Sciences

Awards and Honors

  • Certificate of Appreciation from Assistant Deputy Under Secretary for Health/US Department of Veterans Affairs for contributions to PTSD
  • Danielli Award and President's Award, International Society for Traumatic Stress Studies
  • Anna-Monika Foundation Depression Research Award (shared with Aaron T. Beck, Gerard Sanacora)
  • Joel Elkes Award, American College of Neuropsychopharmacology
  • Exemplary Psychiatrist Award, National Alliance on Mental Illness

Selected Publications

Pietrzak, R. H., Henry, S., Southwick, S. M., Krystal, J. H., & Neumeister, A. (2013). Linking in vivo brain serotonin type 1B receptor density to phenotypic heterogeneity of posttraumatic stress symptomatology. Molecular Psychiatry, 18, 399-401. doi:10.1038/mp.2012.60

Anticevic, A., Gancsos, M., Murray, J. D., Repovs, G., Driesen, N. R., Ennis, D. J., Niciu, M. H., Morgan, P. T., Surti, T. S., Bloch, M. H., Ramani, R., Smith, M. A., Wang, X. J., Krystal, J. H., & Corlett, P. R. (2012). NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia. Proceedings of the National Academy of Sciences of the United States of America, 109, 16720-16725. doi:10.1073/pnas.120849410

Petrakis, I. L., Ralevski, E., Desai, N., Trevisan, L., Gueorguieva, R., Rounsaville, B., & Krystal, J. H. (2012). Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence. Neuropsychopharmacology, 37, 996-1004. doi:10.1038/npp.2011.283

Krystal, J. H., Rosenheck, R. A., Cramer, J. A., Vessicchio, J. C., Jones, K. M., Vertrees, J. E., Horney, R. A., Huang, G. D., & Stock, C. (2011). Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: A randomized trial. The Journal of the American Medical Association, 306, 493-502. doi:10.1001/jama.2011.1080

Murrough, J. W., Huang, Y., Hu, J., Henry, S., Williams, W., Gallezot, J. D., Bailey, C. R., Krystal, J. H., Carson, R. E., & Neumeister, A. (2011). Reduced amygdala serotonin transporter binding in posttraumatic stress disorder. Biological Psychiatry, 70, 1033-1038. doi:10.1016/j.biopsych.2011.07.003

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