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Ronald S. Duman, PhD

 

Ronald S. Duman, PhD

Ronald S. Duman, PhD

Researcher

Clinical Neurosciences Division

See staff directory for contact information.


Academic Appointment

  • Yale University School of Medicine, Professor of Psychiatry

Education

  • University of Texas Medical School, Huston, TX, Neuropharmacology, PhD, 1985
  • College of William and Mary, Williamsburg, VA, BS, Biology, 1976

Expertise and Interests

  • Molecular and cellular mechanisms that mediate long-term effects of psychotrophic drugs and stress
  • Study the molecular mechanisms underlying the regulation of neurotransmitter and neuropeptide receptor expression
  • Role of receptors in drug reward, craving and withdrawal

Membership in Professional Societies

  • Society for Neuroscience
  • American College of Neuropsychopharmacology
  • Biological Psychiatry
  • American Society of Pharmacology & Experimental Therapeutics
  • International Society for Neurochemistry
  • Anxiety Disorders Association of America
  • American Association for the Advancement of Science

Awards and Honors

  • The Elizabeth Mears and House Jamison Professor of Psychiatry and Endowed Chair, 2001
  • NARSAD-Nola Maddox Falcone Prize for outstanding research in depression, 2002
  • NIH Merit Award, 2005 - 2015

Selected Publications

Liu RJ, FS Lee, X-Y Li, F Bambico, RS Duman, and G Aghajanian (2012) BDNF Met allele decreases the density and function of spine/synapses in the prefrontal cortex and blocks the effects of ketamine. Biological Psychiatry 71(11), 996-1005. PMCID: PMC3290730.

Son S, M Banasr, P Licznerski, B Lee, B Voleti, N Li, S Yang, M Choi and RS Duman (2012) Neuritin reverses the neuronal and behavioral deficits caused by chronic stress. Proc Natl Acad Sci USA 109(28),11378-83. PMCID: PMC3396528.

Kang H-J, B Voleti, T Hajszan, G Rajkowska, C Stockmeier, P Licznerski, A Lepack, MS Majik, LS Jeong, M Banasr, H Son, and RS Duman (2012) Decreased expression of synapse related genes and loss of synapses in major depression. Nature Medicine 18(9), 1413-7. PMCID: 3491115.

Duman RS and GK Aghajanian (2012) Synaptic Dysfunction in Depression: Novel Therapeutic Targets. Science 338(6103), 68-72. PMCID-in process.

Li N, RJ Liu, JM Dwyer, M Banasr, BY Lee, H Son, M Iwata, XY Li, G Aghajanian, and RS Duman (2011) NMDA receptor antagonists rapidly reverse the behavioral and morphological deficits caused by chronic stress exposure. Biological Psychiatry 69, 754-761. PMCID: PMC3068225.

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