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PTSD: National Center for PTSD

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Paul Holtzheimer, MD

Paul Holtzheimer, MD

Portrait of Paul Holtzheimer, MD

Deputy Director for Research

Executive Division

See staff directory for contact information.

Academic Appointment

  • Geisel School of Medicine at Dartmouth, Associate Professor of Psychiatry and Surgery


  • Emory University, MS, Clinical Research, 2008
  • University of Washington, Fellowship in Transcranial Magnetic Stimulation, 2004
  • University of Washington, Psychiatry Residency, 2003
  • Dartmouth Medical School, MD, 1999
  • Pacific Lutheran University, BS, BA, 1995

Expertise and Interests

  • Treatment-resistant mood and anxiety disorders
  • Focal brain stimulation (transcranial magnetic stimulation, deep brain stimulation, transcranial direct current stimulation, vagus nerve stimulation)
  • Electroconvulsive therapy
  • Brain imaging of mood and anxiety disorders

Membership in Professional Societies

  • American College of Neuropsychopharmacology
  • Anxiety and Depression Association of America
  • International Society for Traumatic Stress Studies
  • Society of Biological Psychiatry

Awards and Honors

  • George N. Thompson Award for Distinguished Service, Society of Biological Psychiatry
  • Brain Behavior Research Foundation (NARSAD) Independent Investigator Award
  • Brain Behavior Research Foundation (NARSAD) Young Investigator Award

Selected Publications

Sippel, L.M., Holtzheimer, P.E., Friedman, M.J., Schnurr, P.P. (2018). Defining Treatment-Resistant Posttraumatic Stress Disorder: A Framework for Future Research. Biological Psychiatry, online April 10, 2018. doi:10.1016/j.biopsych.2018.03.011.

Holtzheimer, P.E., Husain, M.M., Lisanby, S.H., Taylor, S.F., Whitworth, L.A., McClintock, S., Slavin, K.V., Berman, J., McKhann, G.M., Patil, P.G., Rittberg, B.R., Abosch, A., Pandurangi, A.K., Holloway, K.L., Lam, R.W., Honey, C.R., Neimat, J.S., Henderson, J.M., DeBattista, C., Rothschild, A.J., Pilitsis, J.G., Espinoza, R.T., Petrides, G., Mogilner, A.Y., Matthews, K., Peichel, D., Gross, R.E., Hamani, C., Lozano, A.M., Mayberg, H.S. (2017). Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial. Lancet Psychiatry, 4(11), 839-849. doi:10.1016/S2215-0366(17)30371-1.

Holtzheimer, P.E., Kelley, M.E., Gross, R.E., Filkowski, M.M., Garlow, S.J., Barrocas, A., Wint, D., Craighead, M.C., Kozarsky, J., Chismar, R., Moreines, J.L., Mewes, K., Riva Posse, P., Gutman, D.A., Mayberg, H.S. (2012). Subcallosal cingulate deep brain stimulation for treatment-resistant unipolar and bipolar depression. Archives of General Psychiatry, 69(2), 150-8. doi:10.1001/archgenpsychiatry.2011.1456.

Karsen, E.F., Watts, B.V., Holtzheimer, P.E. (2014). Review of the Effectiveness of Transcranial Magnetic Stimulation for the Symptoms of Post Traumatic Stress Disorder. Brain Stimulation, 7(2), 151-7. doi:10.1016/j.brs.2013.10.006.

Holtzheimer, P.E., Choi, K.S., Franco, A.R., Kelley, M.E., Dunlop, B.W., Hu, X.P., Mayberg, H.S. (2014). Reconciling variable findings of white matter integrity in major depressive disorder. Neuropsychopharmacology, 39(6), 1332-9. doi:10.1038/npp.2013.345.

Members of the press interested in scheduling an interview please see the contact for the media page.

PTSD Information Voice Mail: (802) 296-6300
Also see: VA Mental Health