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Janitza L. Montalvo-Ortiz, PhD

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Janitza L. Montalvo-Ortiz, PhD

Research Biologist

Clinical Neurosciences Division

See staff directory for contact information.

Academic Appointment

  • Yale University School of Medicine, Assistant Professor of Psychiatry


  • Yale University School of Medicine, Department of Psychiatry, Postdoc, 2018
  • Northwestern University School of Medicine, Department of Psychiatry and Behavioral Sciences, Neuroscience, PhD, 2014
  • University of Puerto Rico, Rio Piedras Campus, Biology, BA, 2009

Expertise and Interests

  • Psychiatric genetics
  • Epigenomics
  • Neuroscience
  • Early trauma
  • Post-traumatic stress disorder
  • Substance use disorders

Membership in Professional Societies

  • Society of Biological Psychiatry
  • American Society of Human Genetics
  • International Society of Psychiatric Genetics

Awards and Honors

  • Career Development Award, Department of Veterans Affairs
  • NARSAD Young Investigator Award, The Brain & Behavior Research Foundation
  • Faculty for Excellence and Diversity Initiative Award, Yale University

Selected Publications

Montalvo-Ortiz JL, Gelernter J, Gopalan S, Southwick SM, Krystal JH, Pietrzak RH. Epigenome-Wide Association Study of Posttraumatic Stress Disorder Identifies Novel Loci in U.S. Military Veterans. Accepted. Translational Psychiatry.

Montalvo-Ortiz JL, Cheng Z, Kranzler HR, Zhang H, Gelernter J. (2019). Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European-American Women. Scientific Reports, 15, 9(1), 4660. PMID: 30874594.

Montalvo-Ortiz JL, Zhou H, D'Andrea I, Maroteaux L, Lori A, Smith A, Ressler KJ, Nuñez Y, Farrer, LA, Zhao H, Kranzler HR, Gelernter J. (2018) Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response. Molecular Psychiatry, 23(12), 2277-2286. PMID: 29875475.

Kaufman J, Montalvo-Ortiz JL, Yang BZ, Orr C, Holbrook H, O'Loughlin K., Wang T, Zhao H, Althoff R, Garavan H, Gelernter J, Hudziak J. (2018) Adverse Childhood Experiences, Epigenetic Measures, and Obesity in Youth. Journal of Pediatrics, 202, 150-156. PMID: 30177354.

Montalvo-Ortiz JL, Gelernter J, Hudziak J, Kaufman J. RDoC and translational perspectives on the genetics of trauma-related psychiatric disorders. (2016) American Journal of Medical Genetics Part B Neuropsychiatric Genetics, 171(1),81-91. PMID: 26592203.

Montalvo-Ortiz JL. (2022). Epigenomic Biomarkers of Post-Traumatic Stress Disorder. In N. Youssef (Ed.), Epigenetics of Stress and Stress Disorders. Elsevier.

Kaufman J, Montalvo-Ortiz JL, Lee R. (2019). Child Maltreatment and Psychopathology. In Miu AD, Homberg JR, Lesch, KP (Eds.), Genes, Brain and Emotions: From Resilience to Psychopathology. Oxford, UK: Oxford University Press.

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Also see: VA Mental Health